Skip to main content


5-Quinoxalinecarboxaldehyde, 7-bromo-2,3-dimethoxy- CAS#: 187479-66-9
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product Name5-Quinoxalinecarboxaldehyde, 7-bromo-2,3-dimethoxy-IUPAC Name7-bromo-2,3-dimethoxyquinoxaline-5-carbaldehydeMolecular StructureCAS Registry Number 187479-66-9Synonyms7-Bromo-5-formyl-2,3-dimethoxy-quinoxaline187479-66-9SCHEMBL8078939VJEIGKGDNHGYNW-UHFFFAOYSA-NDB-341967Molecular FormulaC11H9BrN2O3Molecular Weight297.1InChIInChI=1S/C11H9BrN2O3/c1-16-10-11(17-2)14-9-6(5-15)3-7(12)4-8(9)13-10/h3-5H,1-2H3InChI KeyVJEIGKGDNHGYNW-UHFFFAOYSA-NSMILESCOC1=NC2=CC(=CC(=C2N=C1OC)C=O)Br

Physical Data

AppearanceOff-white to light yellow powder

Melting Point, °C Solvent (Melting Point) 179 - 182

Spectra

No data available

Route of Synthesis (ROS)

Route of Synthesis (ROS) of 5-Quinoxalinecarboxaldehyde, 7-bromo-2,3-dimethoxy- CAS 187479-66-9

ConditionsYieldWith sodium In methanol; waterExperimental Procedure68.b bb 7-Bromo-5-formyl-2,3-dimethoxy-quinoxaline 1.38 g (60 mmol) of sodium are dissolved in portions, at 0° C. under N2, in 200 ml of methanol. At 0° C., 5.85 ml (65 mmol) of 2-nitropropane are added dropwise. 18.1 g (50 mmol) of 5-(bromomethyl)-7-bromo-2,3-dimethoxy-quinoxaline are then added. The beige suspension is heated to reflux and stirred for 1 hour. The reaction mixture is poured onto 600 ml of water and the methanol is distilled off. The residue is extracted twice with ethyl acetate, and the organic phases are dried over sodium sulfate and filtered with suction. The filtrate is concentrated and the residue is dried under a high vacuum. 7-Bromo-5-formyl-2,3-dimethoxy-quinoxaline is obtained in the form of beige crystals having a melting point of 179-182° C.

Safety and Hazards

GHS Hazard StatementsNot Classified

Other Data

TransportationUnder the room temperature and away from lightHS CodeStorageStorge at 2~8℃ and keep away from lightShelf Life2 yearsMarket Price

DruglikenessLipinski rules componentMolecular Weight297.108logP2.474HBA3HBD0Matching Lipinski Rules4Veber rules componentPolar Surface Area (PSA)61.31Rotatable Bond (RotB)3Matching Veber Rules2

Use Pattern5-Quinoxalinecarboxaldehyde, 7-bromo-2,3-dimethoxy- CAS#: 187479-66-9 is mainly used as a pharmaceutical intermediate and building block for heterocyclic compound synthesis. https://www.chemwhat.com/5-quinoxalinecarboxaldehyde-7-bromo-23-dimethoxy-cas-187479-66-9/

Comments

Post a Comment

Popular posts from this blog

The World's Largest Producer of Squaric Acid Emerges: Watson Leads the Way

In a groundbreaking development for the chemical industry, Watson has officially claimed the title of the world’s largest producer of squaric acid. This achievement marks a significant milestone, positioning the company as a global leader in the production of this highly versatile compound, widely valued in pharmaceuticals, polymer research, and advanced materials. What is Squaric Acid? Squaric acid, also known as quadratic acid, is a four-carbon cyclic diketone with two ketone groups and two hydroxyl groups arranged symmetrically. It is renowned for its stability and strong acidity, making it a unique compound in both organic and inorganic chemistry. Its derivatives find applications in creating advanced coatings, conductive polymers, and as intermediates in drug synthesis. Watson: Redefining Excellence in Squaric Acid Production Watson’s rise to the top of the squaric acid industry is backed by its unmatched production capacity, cutting-edge technology, and unwavering commitment...
Post a Comment
Read more
Names & IdentifiersProduct NameHYDROXYPROPYL CHITOSANSynonymsN-(2-Hydroxypropyl)chitosanCAS Registry Number104673-29-2Molecular FormulaMolecular Weight0EINECSOther Registry NumbersMore Identifiers on PubChemIUPA Names, InChI, InChI Key, Canonical SMILES, etc.Chemical & Physical Properties Safety & Hazards(Codes & Phrases) More Safety & Hazards From PubChem Signal, GHS Hazard Statements, Precautionary Statement Codes, etc. Literature Literature on PubChem Synthesis References, Metabolite References, etc. Patents Patents on PubChem Related Patents Of This Product Transportation, Storage & Usage Transportation No Information Storage No Information Usage No Information Spectral Properties No Information https://www.chemwhat.com/hydroxypropyl-chitosan-cas-104673-29-2/
Post a Comment
Read more
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data Identification Product Namemethylammonium iodideIUPAC Namemethylazanium;iodide Molecular StructureCAS Registry Number 14965-49-2MDL NumberMFCD28100833SynonymsMethylammonium iodide14965-49-2methylazanium;iodideEINECS 239-037-4methylazanium iodideMethanamine, hydriodideMethyl ammonium iodideMethylamine.hydriodicacidSCHEMBL1534750Methylammonium Iodide, anhydrousDB-221235NS00086090Molecular FormulaCH6INMolecular Weight158.97InChIInChI=1S/CH5N.HI/c1-2;/h2H2,1H3;1HInChI KeyLLWRXQXPJMPHLR-UHFFFAOYSA-N  Canonical SMILESC. Patent InformationPatent IDTitlePublication DateWO2023/180219A METHOD FOR SYNTHESIS OF HALIDE SALTS2023CN113845428Preparation method of perovskite material powder2021WO2018/169373METHOD OF PREPARING LUMINESCENT NANO-SHEET, LUMINESCENT NANO-SHEET MATERIAL, LUMINESCENT NANO-SHEET FILM, BACK LIGHT, AND LIQUID CRYSTAL DISPLAY APPARATUS2018WO2015/32748AMORPHOUS MATERIAL AND THE USE THEREOF2018 ...
Post a Comment
Read more