Skip to main content

Icariin CAS #: 118525-40-9

Icariin CAS #: 118525-40-9
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data

Identification



Product NameIcariinIUPAC Name3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one  Molecular Structurestructure of CAS-118525-40-9CAS Registry Number 118525-40-9EINECS NumberNo available dataMDL NumberMFCD22422519Beilstein Registry NumberNo available dataSynonymsicaritinanhydroicaritin3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-oneicariinAHIICTMolecular FormulaC21H20O6Molecular Weight368.386InChIInChI=1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3  InChI KeyTUUXBSASAQJECY-UHFFFAOYSA-N  Canonical SMILESCC(=CCC1=C2C(=C(C=C1O)O)C(=O)C(=C(O2)C3=CC=C(C=C3)OC)O)C  

Patent InformationPatent IDTitlePublication DateWO2022/104153COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS 2022CN113180043Application of chitin hydrolase inhibitor in regulation of insect growth activity2021CN113024602Phosphate ester derivative of herba epimedii as well as preparation method and application of phosphate ester derivative2021

Physical Data



AppearanceYellow needle crystal or yellow crystalline powderSolubilityNo data availableFlash PointNo data availableRefractive indexNo data availableSensitivityNo data available

Melting Point, °C Solvent (Melting Point) 178 - 180253207 - 208methanol231 - 232methanol

Spectra



Description (NMR Spectroscopy)Nucleus (NMR Spectroscopy)Solvents (NMR Spectroscopy)Frequency (NMR Spectroscopy), MHzChemical shifts, Spectrum1H
dimethylsulfoxide-d6400HMBC (Heteronuclear Multiple Bond Coherence), Spectrum1H, 13Cdimethylsulfoxide-d6No data available

Description (IR Spectroscopy)Solvent (IR Spectroscopy)Temperature (IR Spectroscopy), °CBandspotassium bromide 27Bandspotassium bromide14.85 - 54.85

Description (UV/VIS Spectroscopy)Solvent (UV/VIS Spectroscopy)Comment (UV/VIS Spectroscopy)Absorption Maxima (UV/VIS), nmExt./Abs. Coefficient, l·mol-1cm-1SpectrummethanolNo data available271, 321, 372No available dataAbsorption maxima
methanolNo data available
368No available data

Route of Synthesis (ROS)



Route of Synthesis (ROS) of Icariin CAS #: 118525-40-9

ConditionsYieldWith sulfuric acid; glacial acetic acid at 90℃; for 6h;92%With hydrogen; triethylamine In ethanol; water at 110℃; under 30003 Torr; for 24h; Autoclave;98%

Safety and Hazards



GHS Hazard StatementsNot Classified

Other Data



TransportationStore at room temperature, sealed and away from lightHS CodeNo data availableStorageStore at 2-8℃ for long time, Sealed and away from lightShelf Life1 year

DruglikenessLipinski rules componentMolecular Weight368.386logP4.751HBA2HBD3Matching Lipinski Rules4Veber rules componentPolar Surface Area (PSA)96.22Rotatable Bond (RotB)4Matching Veber Rules2

BioactivityPharmacological Data

1 of 3Comment (Pharmacological Data)Bioactivities presentReferenceCurrent Patent Assignee: AMOREPACIFIC CORP. - WO2007/64085, 2007, A12 of 3Comment (Pharmacological Data)Bioactivities presentReferenceCurrent Patent Assignee: BEIJING SHENOGEN PHARMA GROUP - WO2008/52005, 2008, A23 of 3Comment (Pharmacological Data)Bioactivities presentReferenceCurrent Patent Assignee: LUNAN PHARMACEUTICAL GROUP CO LTD - US2016/250243, 2016, A1

Use PatternIcariin CAS #：118525-40-9 is used Pharmaceuticals and prevent thrombocytopenia,preventing bone marrow suppression
https://www.chemwhat.com/icariin-cas-118525-40-9/

Comments

Post a Comment

Popular posts from this blog

IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data Identification Product Namemethylammonium iodideIUPAC Namemethylazanium;iodide Molecular StructureCAS Registry Number 14965-49-2MDL NumberMFCD28100833SynonymsMethylammonium iodide14965-49-2methylazanium;iodideEINECS 239-037-4methylazanium iodideMethanamine, hydriodideMethyl ammonium iodideMethylamine.hydriodicacidSCHEMBL1534750Methylammonium Iodide, anhydrousDB-221235NS00086090Molecular FormulaCH6INMolecular Weight158.97InChIInChI=1S/CH5N.HI/c1-2;/h2H2,1H3;1HInChI KeyLLWRXQXPJMPHLR-UHFFFAOYSA-N  Canonical SMILESC. Patent InformationPatent IDTitlePublication DateWO2023/180219A METHOD FOR SYNTHESIS OF HALIDE SALTS2023CN113845428Preparation method of perovskite material powder2021WO2018/169373METHOD OF PREPARING LUMINESCENT NANO-SHEET, LUMINESCENT NANO-SHEET MATERIAL, LUMINESCENT NANO-SHEET FILM, BACK LIGHT, AND LIQUID CRYSTAL DISPLAY APPARATUS2018WO2015/32748AMORPHOUS MATERIAL AND THE USE THEREOF2018 ...
Post a Comment
Read more
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data Identification Product NameNickel HydroxideIUPAC Namenickel;dihydrate Molecular StructureCAS Registry Number 12054-48-7EINECS Number235-008-5MDL NumberMFCD00011140Beilstein Registry NumberSynonyms12054-48-7AKOS015903693CS-0089243dihydroxynickelEC 235-008-5EINECS 235-008-5HSDB 1827LS-96321MFCD00011140Nickel dihydroxideNickel hydroxide (II)Nickel hydroxide (Ni(OH)2)Nickel hydroxide (ous)Nickel Hydroxide nanowireNickel(2+) hydroxidenickel(II) dihydroxideNickel(II) hydroxide, for analysisnickel;dihydrateNickelous hydroxideUNII-L8UW92NW6JMolecular FormulaH4NiO2Molecular Weight94.724 InChIInChI=1S/Ni.2H2O/h;2*1H2 InChI KeyAIBQNUOBCRIENU-UHFFFAOYSA-N  Canonical SMILESO.O.   Physical Data AppearanceGreen powder Spectra Description (IR Spectroscopy)Solvent (IR Spectroscopy)Temperature (IR Spectroscopy), °CBandssolid matrix-258 Description (UV/VIS Spectroscopy)Solvent (UV/VIS Spectroscopy)Comment (UV/VIS Spec...
Post a Comment
Read more

A Timeless Fusion - The Lantingji Xu Bookmark produced by ChemWhat

ChemWhat has partnered with British curators and a renowned Hong Kong calligrapher to bring forth, for the very first time, a faithful copper bookmark reproduction of Feng Chengsu's Shenlong Edition of the The Preface to the Orchid Pavilion Gathering — hailed as the greatest calligraphic work under heaven and widely regarded as the Tang dynasty copy closest to Wang Xizhi's original masterpiece. https://www.youtube.com/watch?v=nl-ybtqjJho
Post a Comment
Read more