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以核心技术攻克司美格鲁肽侧链“卡脖子”环节,驱动GLP-1药物高效生产

Watson提供Fmoc-AEEA CAS 166108-71-0或者AEEA-AEEA CAS 1143516-05-5两种中间体选项,确保产品纯度达到99.0%,最大单一杂质不高于0.3%。Watson的Fmoc-Glu-OtBu CAS 84793-07-7或者不带保护的Glu-OtBu CAS 45120-30-7的光学纯度达到99.5%,同时确保最大单一杂质严格限定在不超过0.3%,甚至针对头部药企对杂质毒理研究的“零容忍”需求,更可在不大幅增加成本的前提下定制不超过0.1%的超严苛标准
https://www.youtube.com/watch?v=2R1nrIr-L_M

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