Skip to main content
Tetrahydrothiophene CAS#: 110-01-0
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product NameTetrahydrothiopheneIUPAC NamethiolaneMolecular StructureCAS Registry Number 110-01-0EINECS Number203-728-9MDL NumberMFCD00005476Beilstein Registry Number102392SynonymstetrahydrothiopheneThiolane110-01-0Thiophene, tetrahydro-ThiophaneThiacyclopentaneTetramethylene sulfideThilaneTetrahydrothiophenPennodorant 1013ThiofanThiolanTetrahydrothiofenNSC 5272744EHT13FMDTXSID3047760CHEBI:48458NSC-5272Thiofan TetramethylenesulfidePennodorant 1073Tetrahydrothiofen TETRAHYDROTHIOPHENE-2,2,5,5-D4HSDB 6122EINECS 203-728-9UN2412UNII-744EHT13FMAI3-30989tetrahydro-thiopheneMFCD00005476Tetramethylene sulphideTRIMETHYLENESULFIDETetrahydrothiophene, 99%EC 203-728-9CHEMBL1379TETRAHYDROTHIOPHENE DTXCID8027743NSC5272Tox21_304026AKOS006220479Tetrahydrothiophene, analytical standardUN 2412NCGC00357279-01CAS-110-01-0FT-0659266T0114EN300-105780InChI=1/C4H8S/c1-2-4-5-3-1/h1-4HQ412118Tetrahydrothiophene W-108699Molecular FormulaC4H8SMolecular Weight88.17InChIInChI=1S/C4H8S/c1-2-4-5-3-1/h1-4H2InChI KeyRAOIDOHSFRTOEL-UHFFFAOYSA-NIsomeric SMILESC1CCSC1  

Patent InformationPatent IDTitlePublication DateCN113999131Method for visible light to promote nickel-catalyzed alkyl C-H bonding to prepare amide derivatives2022JP2020/180120CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION, AND METHOD FOR PRODUCING RESIST PATTERN2020 CN112125891N2-selective tetrahydrofuran/tetrahydrothiophene substituted triazole derivative as well as synthesis method and application thereof2020CN1096084627-alkyl-9-alkoxy/mercaptopurine-8-one compound, synthesis method thereof and application of compound in medicines2019WO2018/2031942018

Physical Data

AppearanceColourless liquidBoiling Point118~124°C

Melting Point, °C -96.1 -96.8-96.16-96.06

Boiling Point, °CPressure (Boiling Point), Torr119119760.051121.117760122 - 124760119 - 121

Density, g·cm-3Reference Temperature, °CMeasurement Temperature, °C0.998692014200.9992420

Description (Association (MCS))Solvent (Association (MCS))Temperature (Association (MCS)), °CPartner (Association (MCS))Enthalpy of adsorptionhexane25zeolite YFurther physical properties of the adsorbed molecule-264.16Cu(001)Desorption25 - 2007 percent MoO3/γ-Al2O3 surfaceFurther physical properties of the adsorbed molecule24.9MoO3/γ-Al2O3 (initial)Enthalpy of adsorption

Spectra

Description (NMR Spectroscopy)Nucleus (NMR Spectroscopy)Solvents (NMR Spectroscopy)Frequency (NMR Spectroscopy), MHzFrequency (NMR Spectroscopy), MHzChemical shifts, Spectrum1Hchloroform-d1supporting informationChemical shifts, Spectrum13Cchloroform-d1supporting informationChemical shifts, Spectrum1Hchloroform-d1400supporting information

Description (IR Spectroscopy)Solvent (IR Spectroscopy)Temperature (IR Spectroscopy), °CSpectrumpotassium bromideBandsneat (no solvent)

Description (UV/VIS Spectroscopy)Solvent (UV/VIS Spectroscopy)Comment (UV/VIS Spectroscopy)Absorption Maxima (UV/VIS), nmExt./Abs. Coefficient, l·mol-1cm-1SpectrumN,N-dimethyl-formamide, waterSpectrumcyclohexane200 - 280 nmAbsorption maximacyclohexane202, 2192480, 870Spectrum180 - 230 nm

Route of Synthesis (ROS)

Route of Synthesis (ROS) of Tetrahydrothiophene CAS 110-01-0

ConditionsYieldIn ethanol; water at 20℃; for 2h;Experimental ProcedureTetrachloroauric(III) acid (1.0 g, 2.5 mmol) in 1.3 mL of water was added to 7.8 mL of ethanol andstirred at room temperature. To the resultant solution, 0.44 mL (4.9 mmol) of tetrahydrothiophene was addedslowly, stirred at room temperature for 2 h, and then white precipitate was appeared. The precipitate wascollected by filtration, washed with small amount of ethanol and air-dried to give 0.77 g (2.4 mmol) of whitesolid ((tht)AuCl) in 96% yield.96%In ethanol; water at 20℃; for 0.25h;95%In ethanol; water at 20℃;88%ethanol; water at 20℃;88%

Safety and Hazards

Pictogram(s)SignalDangerGHS Hazard StatementsH225: Highly Flammable liquid and vapor H302: Harmful if swallowed H312: Harmful in contact with skin H315: Causes skin irritation H319: Causes serious eye irritation H332: Harmful if inhaled H412: Harmful to aquatic life with long lasting effects Precautionary Statement CodesP210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P235, and P501(The corresponding statement to each P-code can be found at the GHS Classification page.)

Other Data

TransportationKeep container tightly closed in a dry and well-ventilated place. Keep away from heat andsources of ignition.HS CodeStorageKeep container tightly closed in a dry and well-ventilated place. Keep away from heat andsources of ignition.Shelf Life1 yearMarket Price

DruglikenessLipinski rules componentMolecular Weight88.1735logP1.687HBA0HBD0Matching Lipinski Rules4Veber rules componentPolar Surface Area (PSA)25.3Rotatable Bond (RotB)0Matching Veber Rules2

BioactivityIn vitro: EfficacyQuantitative Results

Toxicity/Safety PharmacologyQuantitative Results

Use Pattern Tetrahydrothiophene CAS#: 110-01-0 is used as an organic solvent, commonly employed in chemical synthesis and laboratory operations, particularly in reactions involving some sulfur compounds.
https://www.chemwhat.com/tetrahydrothiophene-cas-110-01-0/

Comments

Post a Comment

Popular posts from this blog

Overcoming the "Choke Points" in Semaglutide Side Chain Synthesis with Core Technologies to Enable Efficient GLP-1 Drug Manufacturing

Semaglutide, a groundbreaking product in the GLP-1 drug class, owes its extended half-life and enhanced receptor affinity largely to its unique side chain, Ste-Glu-AEEA-AEEA-OSU (CAS: 1169630-40-3) . This side chain covalently modifies the peptide backbone, significantly improving pharmacokinetics and therapeutic performance. However, its complex structure presents two critical synthetic challenges: Precise Assembly of Repetitive AEEA Units: The side chain features consecutive AEEA (aminoethoxyethoxyacetic acid) units, which require stepwise coupling via highly activated intermediates (e.g., AEEA-AEEA). Any impurities or deviations compromise downstream reaction efficiency and may trigger irreversible byproducts. Stereochemistry and Stability of Glutamic Acid (Glu): The glutamic acid component must maintain strict L-configuration, and its carboxyl groups require directional protection (e.g., OtBu) to preserve biological activity. Leveraging deep expertise in peptide chemistry a...
Post a Comment
Read more
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data Identification Product NameBCTA-4NH2IUPAC NameMolecular StructureCAS Registry Number 2559708-42-6Synonyms4,4',4",4"'-(-3,3',6,6'-tetrayl)tetraanilineMolecular FormulaC48H36N6Molecular Weight696.86 Physical Data AppearanceYellow to white powder Spectra No data available BCTA-4NH2 CAS#：2559708-42-6 NMR Route of Synthesis (ROS) No data available Safety and Hazards No data available Other Data TransportationStore at 2-8°C away from light for long time storageStore at 2-8°C away from light for long time storageHS CodeStorageStore at 2-8°C away from light for long time storageShelf Life1 yearMarket Price Toxicity/Safety PharmacologyQuantitative Results Use PatternBCTA-4NH2 CAS#: 2559708-42-6 is an organic compound with a wide range of applications. One of its primary uses is in the field of organic electronics, where it is used as a hole-transport material in organic light-emitti...
Post a Comment
Read more

Watson Chem: Pioneering Advanced Semiconductor Materials for a Sustainable Future

In today’s rapidly advancing technological landscape, the innovation of materials science is driving progress across various high-tech sectors. As a R&D platform of Watson International, Watson Chem has positioned itself at the forefront of semiconductor materials development, becoming a trusted partner for leading global research institutions, energy companies, and high-tech firms. By focusing on extreme purity and stability, Watson Chem specializes in creating cutting-edge semiconductor materials that underpin the breakthrough technologies of tomorrow. Core Competency: Extreme Purity and Stability Watson Chem’s semiconductor materials encompass a range of ultra-pure elements, oxides, sulfides, tellurides, selenides, antimonides, and other semiconductor compounds, available in purity levels ranging from 3N to 7N and beyond. These materials meet the stringent requirements of the most advanced research fields, providing the solid foundation needed for breakthrough innovations. Tru...
Post a Comment
Read more