Skip to main content
PERCHLOROETHYLENE CAS#: 127-18-4
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data

Identification

Product NamePERCHLOROETHYLENEIUPAC Name 1,1,2,2-tetrachloroethene  Molecular StructureCAS Registry Number 127-18-4EINECS Number204-825-9MDL NumberMFCD00000834SynonymsTETRACHLOROETHYLENETetrachloroethene127-18-4Perchlorethylene1,1,2,2-TetrachloroethyleneEthylene tetrachlorideCarbon dichlorideTetrachloraethenPerchloorethyleen, perEthylene, tetrachloro-PerchloroetheneRcra waste number U210Percloroetilene Perclene TGCzterochloroetylen Tetrachloroethylene (IUPAC)Perchloorethyleen, per EINECS 204-825-9Tetrachloroethylene RCRA waste no. U210UNII-TJ904HH8SNEPA Pesticide Chemical Code 078501BRN 1361721TJ904HH8SNTETRACHLOROETHYLENE-1-13CNSC-9777EC 204-825-94-01-00-00715 (Beilstein Handbook Reference)MFCD0000083425135-99-3Tetrachloroethene 100 microg/mL in MethanolNema (VAN)WLN: GYGUYGGTTE (CHRIS Code)Freon 1110Tetrachlooretheen(DUTCH)Tetrachloraethen(GERMAN)bmse000633Czterochloroetylen(POLISH)1,2,2-TetrachloroethyleneC2-Cl4SCHEMBL23022BIDD:ER03461,1,2,2-tetrachloro-ethenePerchloorethyleen, per(DUTCH)Perchloraethylen, per(GERMAN)Perchlorethylene, per(FRENCH)Perchloroethylene Reagent Grade1,1,2, 2-TetrachloroethyleneTetrachloroethylene, >=99.5%Eteno, 1,1,2,2-tetracloro-TETRACHLOROETHYLENE Tetrachloroethylene, UV/IR-GradeEthene, 1,1,2,2-tetrachloro-TETRACHLOROETHYLENE perchloroethylene (tetrachloroethylene)Tetrachloroethylene, anhydrous, >=99%Tetrachoroethylene; see PerchloroethyleneCAS-127-18-4Perchloroethylene; (Tetrachloroethylene)Tetrachloroethylene Tetrachloroethylene, for HPLC, >=99.9%Tetrachloroethylene, ReagentPlus(R), 99%Tetrachloroethylene, for synthesis, 99.0%Tetrachloroethylene, ACS reagent, >=99.0%EN300-19890Tetrachloroethene 1000 microg/mL in MethanolTetrachloroethene 5000 microg/mL in Methanol1,1,2,2-Tetrachloroethylene (ACD/Name 4.0)Tetrachloroethylene, SAJ first grade, >=98.0%Tetrachloroethylene, SAJ special grade, >=99.0%Tetrachloroethylene, UV HPLC spectroscopic, 99.9%TETRACHLOROETHYLENE (PERCHLOROETHYLENE) Tetrachloroethylene, Ultrapure, Spectrophotometric GradeMolecular FormulaC2Cl4Molecular Weight165.8InChIInChI=1S/C2Cl4/c3-1(4)2(5)6  InChI KeyCYTYCFOTNPOANT-UHFFFAOYSA-N  Canonical SMILESC(=C(Cl)Cl)(Cl)Cl  

Patent InformationPatent IDTitlePublication DateCN111454122Method for eliminating hydrogen chloride by catalytic cracking of chloralkane2020WO2014/62255METHOD OF PREPARING HALOGENATED SILAHYDROCARBYLENES2014WO2010/45104PYRROLOPYRIDAZINE DERIVATIVES2010US6362383Hydro-fluorination of chlorinated hydrocarbons2002

Physical Data

AppearanceColorless, clear and no mechanical impurities

Melting Point, °C Comment (Melting Point)13.5Mol(s) H2O-22.35-22.18-23.5-19

Boiling Point, °CPressure (Boiling Point), Torr72 - 7316012255150.015121.1121.1121760.051121

Density, g·cm-3Measurement Temperature, °C1.61273261.6227201.6144924.991.6224.841.614824.99

Description (Association (MCS))Solvent (Association (MCS))Temperature (Association (MCS)), °CPartner (Association (MCS))Enthalpy of adsorptiongaseous matrixcalcined ordered mesoporous silica MCM-41Adsorption isothermgaseous matrix86.84calcined ordered mesoporous silica MCM-41Adsorption and desorption isotherms24.84calcined ordered mesoporous silica MCM-41Adsorption and desorption isotherms24.84Cr3+-exchanged natural clinoptilolite from UkraineEnthalpy of adsorptiongaseous matrixCr3+-exchanged natural clinoptilolite from Ukraine

Spectra

Description (NMR Spectroscopy)Nucleus (NMR Spectroscopy)Solvents (NMR Spectroscopy)Frequency (NMR Spectroscopy), MHzChemical shifts13Ctetrahydrofuran-d8Spectrum13CChemical shifts13C75.5CIDNP13C

Description (IR Spectroscopy)Solvent (IR Spectroscopy)Temperature (IR Spectroscopy), °CSpectrumBandssolid matrix-269.16Bandssolid Ar-261.15SpectrumnujolReflection spectrumSpectrum24.85

Description (UV/VIS Spectroscopy)Solvent (UV/VIS Spectroscopy)Comment (UV/VIS Spectroscopy)Absorption Maxima (UV/VIS), nmExt./Abs. Coefficient, l·mol-1cm-1Spectrumhexaneconcentration dependenceSpectrumgas190 - 290 nmAbsorption maximavarious solvent(s)258.515488.1Absorption maximaethyl acetate25915136Absorption maximadioxane259.59550

Route of Synthesis (ROS)

Route of Synthesis (ROS) of PERCHLOROETHYLENE CAS 127-18-4

ConditionsYieldWith hydrogen fluoride; chlorine; antimony pentafluoride at 126 - 148℃; under 17251.7 - 20252 Torr; for 7.1h;A 51.5%B 44%With hydrogen fluoride; antimony pentafluoride at 145 - 148℃; under 19126.9 Torr; for 4.6h;A 27.7%B 39.8%With hydrogen fluoride; antimony pentafluoride at 106 - 147℃; under 16126.6 - 18001.8 Torr; for 5.3h;Experimental ProcedureExample 4 (comparative) In this experiment, the same catalyst and apparatus as the previous experiment were used. A series of reactions were carried out in the autoclave using the same catalyst. Catalyst fluorination : Antimony pentachloride was added to the autoclave and the autoclave was sealed. Anhydrous hydrogen fluoride (192.8g, 9.64m) was then added in aliquots, venting through the scrubber chain, as required. The autoclave was then heated over 4 hours to 117C and allowed to cool. Run 1: Perchloroethylene (59.8g, 0.361m) was charged to the autoclave. The autoclave was then heated to 106C over 2 hours and the pressure rose to 2.4 MPa (23.0 barg). Venting was then commenced through the scrubber chain. The autoclave was then further heated to 141C over 3.3 hours, while the pressure was maintained between 2.15-2.40 MPa (20.5-23.0 barg).A 21.1%B 30.5%

Safety and Hazards

Pictogram(s)SignalWarningGHS Hazard StatementsH351: Suspected of causing cancer H411: Toxic to aquatic life with long lasting effects Precautionary Statement CodesP203, P273, P280, P318, P391, P405, and P501(The corresponding statement to each P-code can be found at the GHS Classification page.)

Other Data

TransportationUnder room temperature away from lightHS CodeStorageUnder room temperature away from lightShelf Life1 yearMarket Price

DruglikenessLipinski rules componentMolecular Weight165.834logP3.026HBA0HBD0Matching Lipinski Rules4Polar Surface Area (PSA)0Rotatable Bond (RotB)0Matching Veber Rules2

Quantitative Results1 of 262Comment (Pharmacological Data)Bioactivities presentReferenceProcess for the preparation of dibenzothiepin derivative2 of 262Comment (Pharmacological Data)Bioactivities presentReference 3 of 262Comment (Pharmacological Data)Bioactivities presentReferenceProcess for the production of polyfunctional cyanic acid esters4 of 262Comment (Pharmacological Data)Bioactivities presentReferencePROCESS FOR PURIFYING PENTAFLUOROETHANE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF5 of 262Comment (Pharmacological Data)Bioactivities presentReferenceAntifungal paints and coatings

Use PatternPERCHLOROETHYLENE CAS#: 127-18-4 can be usde in metal sur face cleaning,clothes dry cleaning,fossil fuel extracting ,medicine producing ,organic synthesizi ng,and oil,rubber,resin alkaloids,wax dissolving.
https://www.chemwhat.com/perchloroethylene-cas-127-18-4/

Comments

Post a Comment

Popular posts from this blog

Overcoming the "Choke Points" in Semaglutide Side Chain Synthesis with Core Technologies to Enable Efficient GLP-1 Drug Manufacturing

Semaglutide, a groundbreaking product in the GLP-1 drug class, owes its extended half-life and enhanced receptor affinity largely to its unique side chain, Ste-Glu-AEEA-AEEA-OSU (CAS: 1169630-40-3) . This side chain covalently modifies the peptide backbone, significantly improving pharmacokinetics and therapeutic performance. However, its complex structure presents two critical synthetic challenges: Precise Assembly of Repetitive AEEA Units: The side chain features consecutive AEEA (aminoethoxyethoxyacetic acid) units, which require stepwise coupling via highly activated intermediates (e.g., AEEA-AEEA). Any impurities or deviations compromise downstream reaction efficiency and may trigger irreversible byproducts. Stereochemistry and Stability of Glutamic Acid (Glu): The glutamic acid component must maintain strict L-configuration, and its carboxyl groups require directional protection (e.g., OtBu) to preserve biological activity. Leveraging deep expertise in peptide chemistry a...
Post a Comment
Read more
IdentificationPhysical DataSpectraRoute of Synthesis (ROS)Safety and HazardsOther Data Identification Product NameBCTA-4NH2IUPAC NameMolecular StructureCAS Registry Number 2559708-42-6Synonyms4,4',4",4"'-(-3,3',6,6'-tetrayl)tetraanilineMolecular FormulaC48H36N6Molecular Weight696.86 Physical Data AppearanceYellow to white powder Spectra No data available BCTA-4NH2 CAS#：2559708-42-6 NMR Route of Synthesis (ROS) No data available Safety and Hazards No data available Other Data TransportationStore at 2-8°C away from light for long time storageStore at 2-8°C away from light for long time storageHS CodeStorageStore at 2-8°C away from light for long time storageShelf Life1 yearMarket Price Toxicity/Safety PharmacologyQuantitative Results Use PatternBCTA-4NH2 CAS#: 2559708-42-6 is an organic compound with a wide range of applications. One of its primary uses is in the field of organic electronics, where it is used as a hole-transport material in organic light-emitti...
Post a Comment
Read more

Watson Chem: Pioneering Advanced Semiconductor Materials for a Sustainable Future

In today’s rapidly advancing technological landscape, the innovation of materials science is driving progress across various high-tech sectors. As a R&D platform of Watson International, Watson Chem has positioned itself at the forefront of semiconductor materials development, becoming a trusted partner for leading global research institutions, energy companies, and high-tech firms. By focusing on extreme purity and stability, Watson Chem specializes in creating cutting-edge semiconductor materials that underpin the breakthrough technologies of tomorrow. Core Competency: Extreme Purity and Stability Watson Chem’s semiconductor materials encompass a range of ultra-pure elements, oxides, sulfides, tellurides, selenides, antimonides, and other semiconductor compounds, available in purity levels ranging from 3N to 7N and beyond. These materials meet the stringent requirements of the most advanced research fields, providing the solid foundation needed for breakthrough innovations. Tru...
Post a Comment
Read more